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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23d29971a7427db3c14351157df8b61e865dc1ed9093829d829e6464d33ca135' 
  AND token = 'EbaQFYilhTRWm+by7rNTxl4PM8OMyN0RuxrEsPaWXDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}