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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '386b94c613980f249b30b85c50cf382b08683e3b2bbfb9c75947a5ab79c40306' 
  AND token = 'dge5m5Qp5ECE1ESYSkEZEqd9jNS0Dagl/Wv4OpHI8Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}