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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed06e695645fc62869aef084aaccf74ed078dea871e3ba2b3c5f281768311ab8' 
  AND token = 'E0H7qZP7pkjRCpx9njPweKeryKlVcN1ulScR08FCq0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}