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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d46c82e2e0e9367564a72e533c41322e3646eefc233d007716362857f71c549' 
  AND token = 'bL1urAt6Df5QhCmrV/yfBTPmhvV33B1aXK9+W2jFskg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}