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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290dff7f7d8f019d3aee64a927afe350b703140bb3c317bfd625e180be977590' 
  AND token = '/sKeGW5FF61SL+8u0R+MD9KG2kZIob/mKKr9cCh7G0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}