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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ec20bf49176c47604af7dc37c187cf63583431587fba60a8d020a01dac93c3' 
  AND token = 'mWIT9VPfOg9ACGsVi/PouyLj27BvJQ2yTTVgXg2EyM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}