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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727203d009c9bcdb21a5aacdba9866d8b5137507215e64f53d4b970efabac2a4' 
  AND token = '7Hpl+DTzPhWx6jD1R0QU1BVQ2rsUVhSr4NPXYeLyGi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}