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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10521686a44d8ebbcbf582dbc2e29bcd2b7555b86b722295786f3c86255a651d' 
  AND token = 'UmD1OFpZv5ULkOY1aEjvxqDPiEbkccAWhb8CASedXSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}