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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4416babd8a557dd6001b5e7b05b62763e6ea9b9707b3250e12a4426cab6da75' 
  AND token = 'poScU1Y8diwpM6CdbkARZ5T/CaLfdqnWbNZUcLTMBlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}