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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b4679cb758a3df87b9a5a7a8d7069d3975288d9369c0034208c0a4d16232ec' 
  AND token = 'wnLVju0lVR0Y2wwp7WS/JG9C5xxjE8UVvW0yC+k4GZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}