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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd2223a9a62f50a75febf34818f55da0f4c22dec9c6b1d02ded18b821ca269c' 
  AND token = 'Yd6SgLsaQayNGS4rYY1U+x9Cqe7W+3QKJYYg/bUzpTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}