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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c0b2cad01854ff7e1dab0e0798a22f7ef3c4251ef0235625415cd4e7ad6761' 
  AND token = 'TznFAjdnvOKrDyB/K1gClVmfqCm94pgPK+sbN7NDnPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}