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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e61818c7e527fc3223efb7d02e48b9ea72b788260ca28eb3f3a8de12e569918' 
  AND token = 'uWP/+UaOslsS+3RPUqh59voSklzkC45d8Z7EMB94cBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}