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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '603f0794cd44bbb84f2d046069784b089a754626a0d400c9e45e858eb88eab36' 
  AND token = 'qrn3NWVRK96vTFJd1lDbQVphPBI23nBOS1iyTcX+vRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}