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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5063c3a15b35b541f371dc6b7acc2984aef072c596e1f36b6d030564e3e0b441' 
  AND token = 'KlhHeO++xU9fKFUzg04st3K2PKwr4d1+dinUqe7SaiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}