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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6aed9bb99c88dbddbb6a494c0fc9050e131e2b56876aacee9146b4b534fded5' 
  AND token = 'rqnzx8Kvmqqi2t3/O/21OG3xR7R6G6NtHjh1Y4SqixU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}