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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c6315e5052517f3c6e23cfd9dab4b56c909f551e97849032d5881667c61bf8' 
  AND token = 'vPZls0kKl+Xkk2SMoIsRbd3NUSGez9Ft1HcXPqxX5I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}