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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e016ff0d04cc36b900f6aa460a71ece2407b9cd2fc348a0f3f250287e035e6' 
  AND token = '0JYP0cfRhdr5fLuAAYCG8PnCPTceKyPfp8/ojhduf78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}