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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ed4cf84af71ba9666701c8b6bf2ae54868430477273af427df5f0d99c824fd' 
  AND token = 'o5/3ZWtSR1cz0hlbdZuhF0TOxAT9X0/ANi/+unGjRgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}