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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '879ab8111551979adcba2c27432cd40a271fc10c2ed30872edee672722ca3cd8' 
  AND token = 'OuOgYWJVN6Xz3vyS8UofD4AT5S09BSNgowuVKE4LZ4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}