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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ba5b311d920a91270909c1d65e43be157237f48260672d3f24c1ca8444a4bbb' 
  AND token = 'vLglPe6ZRtWZmplDu+yZnJ0nSg4jvxNxA6sG76MvIj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}