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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8377604608268b7103eebfd0d4f5f61440b7b07feb051cc413ff5dba7bc6aeb' 
  AND token = '+w/dFvRyy6yupremevzQioNfoRmIQtxRxGuy53LTeoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}