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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf8611eef58f36f32dcbacfb6b6e34e6c1aa581fce23077f250c32762d1e35b5' 
  AND token = 'MQqe0eB/goAHRp/+ccU8m46/CwIeWtDCr0AZpZ+wqoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}