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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2425f0433d119ad5ca1c236dda1afbcd7d4f61626e2112ac9882e48d1d26ed9b' 
  AND token = 'JiHsVRtaKkZFpsJn8dc92qq1ZYwxp2dn1qlCOmW8Y4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}