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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2c101c2e99f75ee407f8121d7bae60f9c6efcd9ef6a295f648bc49c1a51ec0' 
  AND token = '+PAhb43TXRX8h2nyE96eSniIDzQF3OkhKtlnP4+HBXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}