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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2cc7c914efab140a5255c95049c29c0524e9e10cb27bab759f0a8eef87878b' 
  AND token = '+mEtUC4yPywi+DZ1PlLaW4SnWNcw5qM1QYm+GQtmTwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}