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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f3cc5b3fd55fa927b945c283515594a82a08574b60cc5ee01385d04349849b1' 
  AND token = '15+7U+cU8P7uVAwbw/c+4bUrl/v4whn82dAppdeG4Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}