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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c31269ed92e8e39acf843f83db00a4ef6ff29f2d7fe32473d5dedf0cf6a95314' 
  AND token = 'VwgzkIb9Tx5h3jWMFqAP6rgpipN2V+T/wRNZMewwsYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}