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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75d8a07aef214b3a1d93abab19a4d6c50b73f7cf04940d16e486d8189425186f' 
  AND token = '182XEjZCIyULv57Lz5zze16ltyn39U8qshEtukLHGSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}