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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0451d0b2a8b746e2d2610b1ebf62c5d94e73449aba49fda177795d25ea72b6b9' 
  AND token = 'om3Q7ex/Afw2bZrmQR+EsrkXS+f1EPO/jvbOzea6aN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}