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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '442a9869f2cb3b2854408ff7ba56b04fca511baeab95e05a39d64fd09a0019e3' 
  AND token = 'U2nYv5T50lkHnH/qjIPnW41f8UO4WTzvFP3z62wCaig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}