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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b0c5efe1ef7eb52d4b86a5961d963f428d914f08db55a3ff422bb7d1f7a11f' 
  AND token = '3dZbOf0D0VpXKowkl5BjJNfS4hWEJunnPyE91gx0sHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}