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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3ad4cb490fd2a7eaf8d2ba1485a507e1f29df978d41afa08e11c3ecf854a9b' 
  AND token = 'bCbzLtrHXwHDAODrRExat/nfSMXXVxIpdqmk1D9OUzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}