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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b9a491a3c6f81495e15ecf57e7fb4dff3aea69d9edbd593b5d161636d3e752' 
  AND token = 'sbGRpRdkkSCvDknmLXFv0faqVd90lkTvJhRXZ8lHRLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}