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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c4f7888333cd0af76cdee0531cb03ae6231df85a8c048b65fb78cccd913332' 
  AND token = 'GwWDbWt/jIZFqDW2SQJvIdWb7nv/VJ4h5eD6VBLfEWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}