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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2980a3bda41b11b9cb08ebe574daf00321566f5b305db7bec8270145afbe6eb' 
  AND token = '4CwJ8Pl2UzkMziFoWRsLINWRdwcNk5LBLeLAnq3/BTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}