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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9af2d8cb1025085ad7dab4c16db6498dcc13a03e7be6b60c144a3b1a490b46e2' 
  AND token = 'v6ZEOBS0Vfahh+CvUmalB4gxjUTigx3unV4D+Cu0Ygw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}