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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa9c2520e7ae6799331e3ca30538b09a8d3ed88229524d704b11b4d7d0d51306' 
  AND token = 'ndtJTxlZX/cxqQtAeeeWh5fYs5V0uka3qkaNIU4CF3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}