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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb0b1e347f04ae220a1dbcc5a9c86773bb4e92019b48c5d77e4075548d73708' 
  AND token = '4Ms+OTfQlbEBnpjWb+B4gCf1v7h7i7IpzY+v23GLb70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}