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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f7220dd63290653087e8ddff6275267bf27d763eb0c7edd272d1b2a8d5dd73' 
  AND token = 'M5U/3llmyNbHtEvz2snK52b/umTtpXoLh1EjrVrYrc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}