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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3cedf558ea1d4ce395c028074f6b642ab12c6c6011a645ffa86adedf0149b02' 
  AND token = 'WENo3h5o9OU8a8qx+bBVvfA7KE6oLkv2uEhKwzoJwcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}