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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4992cd515b310806d14e36ae29a16065591b5d3070d0e99734bc811435a1a687' 
  AND token = 'sIePLpxDEQC8j/AfHksJCooVRSQ2UY0qsl39BR6n3+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}