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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363f0a584d10f3c9a02807f1673c44f5edf3e1c01e0e2d10976400fe387229b3' 
  AND token = 'mCrlzBB00T4DxfiY4NTpJzPlY+EGwvyl88uY0kvfdwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}