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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b9bbea386ede2907e1b6952b81219eaec80e76d28b6a2e19ea1b25b8672111' 
  AND token = 'f9JcQ5AIBpLBp9lASZ6Sx8Zgm1JJizNehSv1DmrIVNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}