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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49de07ca07c2234743cf36f21a5dcf6000e9eed553f84be8394f2ffa24249db' 
  AND token = 'Bh8Zxb2oFdd+qBqPIyErhAOdJ+LY7rwXcypNy8QC4Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}