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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5f2446c324d2e141b9214e39b07435da4047911de4eb4b7a81f446f146c6396' 
  AND token = '/VLdMugaekU2eMh5ZUo9ep5rPC+2C/i4Lk/3sPB4c68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}