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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246ccc89e78e3c01b616a191cbe9be2680b18b44f1020ecaaea0a3709a3241f3' 
  AND token = 'OLMDpR+YIfAML/DAyrTzYODc5ZfDPBn5fZ7NtvzI9H0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}