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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f822e8143cb96b61d1664d9cab85f714db0d74184c4934758eb209d3b7f85e1' 
  AND token = 'w1BaQ8dAR2X/qEoCfloj+DsaTe+Mgw4KrF93t1ARCvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}