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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f21ecb2b13d5c1dd0c2394d31c9b27f4bb6457af831623b0917b675af42850c' 
  AND token = 'LPpfK+d67ub+VRF5WF4McEhJErhNbzBy6qTyQ5MCovM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}