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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ed1d8db0088b5473fb455150f18adeb43d457d62329ba0affb5a3da001c67d' 
  AND token = 'lcoG/JKtvhJQs+xN/H5xy7q5WBywyvgiobNXoaXTk2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}